KDIGO Clinical Practice Guideline for ADPKD
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The KDIGO Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD) represents the first KDIGO guideline on this subject. The guideline was recently made available for public review and was published in 2025.
The guideline offers updated recommendations on therapies to slow disease progression, while stressing the importance of shared decision-making and individualised care.
Some of the chapters include information on:
- Therapies to delay the progression of kidney disease (chapter 4)
- Polycystic liver disease (chapter 5)
- Lifestyle and psychosocial aspects (chapter 7)
- Pregnancy and reproductive issues (chapter 8)
- Recommended checklist of issues to discuss at the beginning of the patient journey (appendix 2)
The ADPKD Guideline is co-chaired by Olivier Devuyst, MD, PhD (Switzerland), and Vicente Torres, MD, PhD (United States). Patient representatives of PKD International/ERKNET were involved in the guideline development.